Link between Periodontal Disease and Diabetes
Journal of Bacteriology and Virology
;
: 52-56, 2016.
Article
in Korean
| WPRIM
| ID: wpr-221986
ABSTRACT
Diabetes mellitus (DM) is a complex disease with various systemic and oral complications including periodontitis. Periodontitis is a disease that leads to destruction of the soft and hard tissues of periodontium, which can result in periodontal bone loss and tooth loss. Although the etiology for periodontitis is bacterial plaque, the host immune response also mediates the destruction of periodontal tissues. DM is related to the development, progression and severity of periodontitis. There are several factors potentially contributing to the development of periodontitis in DM patients 1) altered immune function, 2) hyperglycemia and advanced glycation end products, and 3) altered lipid metabolism. With limited number of studies, the potential mechanisms involved in the development of DM in periodontitis have also been suggested. DM clearly increases the risk of periodontitis and biological mechanisms have been illucidated. Less clear is the impact of periodontitis on the development of DM. It is possible that periodontitis may serve as initiators or propagators of insulin resistance in a way similar to obesity, thereby aggravating glycemic control.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Periodontal Diseases
/
Periodontitis
/
Periodontium
/
Insulin Resistance
/
Alveolar Bone Loss
/
Tooth Loss
/
Diabetes Mellitus
/
Lipid Metabolism
/
Hyperglycemia
/
Obesity
Limits:
Humans
Language:
Korean
Journal:
Journal of Bacteriology and Virology
Year:
2016
Type:
Article
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