Needle Revision with and without Mitomycin C for the Teatment of Failed Filtering Blebs after Trabeculectomy
Journal of the Korean Ophthalmological Society
;
: 1087-1092, 2006.
Article
in Korean
| WPRIM
| ID: wpr-222070
ABSTRACT
PURPOSE:
To evaluate the effects of needle revision (NR) with and without mitomycin C (MMC) for failed filtering blebs after trabeculectomy, and to identify risk factors for failure.METHODS:
Thirty-one eyes whose intraocular pressure (IOP) did not decrease after cutting of scleral flap sutures were recruited. NR was performed with a 26-gauge needle under a slit-lamp. Immediately following NR, 15 eyes received subconjunctival injection of 0.002 mg (0.02 mg/ml) MMC at the adjacent conjunctiva.RESULTS:
First NR was done at 1.3+/-1.2 months (range, 0.2~6.5 months) after trabeculectomy, and a mean of 1.6+/-1.6 NRs per patient were done. The follow-up period was 24.4+/-20.4 months (range, 6.0~87.4 months) after the last NR. Pre-NR mean IOP was 27.9+/-11.6 mm Hg and post-NR final IOP was 18.8+/-13.0 mm Hg (p=0.005). The success rate, defined as IOP 25 mm Hg showed a higher failure rate, though with no statistical significance (p=0.141 and p=0.173, respectively).CONCLUSIONS:
NR followed by subconjunctival injection of MMC is an effective and safe method for the treatment of the failed filtering blebs after trabeculectomy. Trabeculectomy without adjunctive MMC and pre-NR IOP higher than 25 mmHg were risk factors for failure of NR.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sutures
/
Trabeculectomy
/
Risk Factors
/
Follow-Up Studies
/
Blister
/
Mitomycin
/
Conjunctiva
/
Intraocular Pressure
/
Needles
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2006
Type:
Article
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