In Thyroid Cancer Patients, Is Preoperative FNAB-C Reliable for Prediction of Lateral Cervical LN Metastasis? / 대한내분비외과학회지
Korean Journal of Endocrine Surgery
;
: 76-80, 2014.
Article
in Korean
| WPRIM
| ID: wpr-222303
ABSTRACT
PURPOSE:
The goal of this study was to evaluate the diagnostic accuracy of preoperative fine needle aspiration biopsy cytology (FNAB-C) in predicting lateral lymph node metastasis in papillary thyroid cancer patients.METHODS:
A total of 592 patients who underwent thyroid cancer surgery and intra-operative lateral cervical LN frozen section or RND, from January 2002 to December 2011, were evaluated retrospectively. Among them, 228 cases had suspicious findings in FNAB-C of lateral nodes. We reviewed their radiological and pathological reports.RESULTS:
Intra-operative frozen section examination was performed in 540 cases and RND was performed in 314 cases. This study included 534 women (83.4%) and 106 men (16.6%). Patients' ranged in age from 9 to 83 years (mean, 45.65 years). FNAB-C was performed in 228 cases. The sensitivity and specificity of FNAB-C was 71.5% and 78.6%, respectively; 35.9% of cases had a false negative result. The combination of FNAB-C and intra-operative frozen section test sensitivity and specificity was 87.2% and 93.6%, respectively.CONCLUSION:
The results for sensitivity in FNAB-C actually appear low, and false negative results were very high. In papillary thyroid cancer in patients with FNAB-C, even if the result is negative, if lymph node metastasis is suspected based on radiologic evidence, frozen section examination should be performed for determination of metastasis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Biopsy
/
Thyroid Neoplasms
/
Retrospective Studies
/
Sensitivity and Specificity
/
Biopsy, Fine-Needle
/
Frozen Sections
/
Lymph Nodes
/
Neoplasm Metastasis
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Endocrine Surgery
Year:
2014
Type:
Article
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