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A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel
Article in En | WPRIM | ID: wpr-222444
Responsible library: WPRO
ABSTRACT
Paragonimiasis is an infectious disease caused by trematodes of the genus Paragonimus. This trematode can be treated successfully with praziquantel in more than 90% of the cases. Although praziquantel is generally well tolerated, anaphylactic reactions to this drug have been reported in a few cases. We report here a 46-year-old Korean female with paragonimiasis, presumed to be due to Paragonimus westermani, who displayed an allergic reaction to praziquantel and resistance to triclabendazole treatment. The patient was successfully treated with praziquantel following a rapid desensitization procedure. Desensitization to praziquantel could be considered when no alternative drugs are available.
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Full text: 1 Index: WPRIM Main subject: Paragonimiasis / Paragonimus / Praziquantel / Benzimidazoles / Drug Resistance / Desensitization, Immunologic / Treatment Outcome / Drug Hypersensitivity Limits: Animals / Female / Humans Language: En Journal: The Korean Journal of Parasitology Year: 2011 Type: Article
Full text: 1 Index: WPRIM Main subject: Paragonimiasis / Paragonimus / Praziquantel / Benzimidazoles / Drug Resistance / Desensitization, Immunologic / Treatment Outcome / Drug Hypersensitivity Limits: Animals / Female / Humans Language: En Journal: The Korean Journal of Parasitology Year: 2011 Type: Article