Pachydermoperiostosis in a 19 Year-old Boy Presenting as an Acromegaly-like Syndrome / 대한소아내분비학회지
Journal of Korean Society of Pediatric Endocrinology
;
: 213-219, 2004.
Article
in Korean
| WPRIM
| ID: wpr-222685
ABSTRACT
A nineteen year-old boy with progressive enlargement of the joints and distal extremities, clubbing, coarse facial features and hyperhidrosis was investigated. In physical examination, thickening of the scalp with furrowing (cutis verticis gyrata) and greasy thickening of skin (pachyderma) was prominent. His endocrine profile was normal. Radiological studies demonstrated bilateral symmetrical periosteal new bone formation with acroosteolysis and incidental microadenoma of pituitay gland. After extensive investigation to exclude systemic and endocrine causes, the patient was diagnosed as pachydermoperiostosis (PDP). PDP is a rare syndrome manifested clinically by finger clubbing, extremity enlargement, hypertrophic skin changes, and periosteal bone formation. The pathogenesis of the disorder has not been clarified though few endocrine abnormalities were seen. To aware of these clinical phenotype would help to differentiate PDP from acromegaly.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteoarthropathy, Primary Hypertrophic
/
Osteogenesis
/
Phenotype
/
Physical Examination
/
Scalp
/
Skin
/
Acromegaly
/
Acro-Osteolysis
/
Extremities
/
Fingers
Limits:
Humans
/
Male
Language:
Korean
Journal:
Journal of Korean Society of Pediatric Endocrinology
Year:
2004
Type:
Article
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