Estimation of T2* Relaxation Times for the Glandular Tissue and Fat of Breast at 3T MRI System
Journal of the Korean Society of Magnetic Resonance in Medicine
;
: 1-6, 2014.
Article
in English
| WPRIM
| ID: wpr-223489
ABSTRACT
PURPOSE:
T2* relaxation time which includes susceptibility information represents unique feature of tissue. The objective of this study was to investigate T2* relaxation times of the normal glandular tissue and fat of breast using a 3T MRI system. MATERIALS ANDMETHODS:
Seven-echo MR Images were acquired from 52 female subjects (age 49 +/- 12 years; range, 25 to 75) using a three-dimensional (3D) gradient-echo sequence. Echo times were between 2.28 ms to 25.72 ms in 3.91 ms steps. Voxel-based T2* relaxation times and R2* relaxation rate maps were calculated by using the linear curve fitting for each subject. The 3D regions-of-interest (ROI) of the normal glandular tissue and fat were drawn on the longest echo-time image to obtain T2* and R2* values. Mean values of those parameters were calculated over all subjects.RESULTS:
The 3D ROI sizes were 4818 +/- 4679 voxels and 1455 +/- 785 voxels for the normal glandular tissue and fat, respectively. The mean T2* values were 22.40 +/- 5.61 ms and 36.36 +/- 8.77 ms for normal glandular tissue and fat, respectively. The mean R2* values were 0.0524 +/- 0.0134/ms and 0.0297 +/- 0.0069/ms for the normal glandular tissue and fat, respectively.CONCLUSION:
T2* and R2* values were measured from human breast tissues. T2* of the normal glandular tissue was shorter than that of fat. Measurement of T2* relaxation time could be important to understand susceptibility effects in the breast cancer and the normal tissue.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Relaxation
/
Breast
/
Breast Neoplasms
/
Magnetic Resonance Imaging
Limits:
Female
/
Humans
Language:
English
Journal:
Journal of the Korean Society of Magnetic Resonance in Medicine
Year:
2014
Type:
Article
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