Chronic Graft-Versus-Host Disease Mimicking Psoriasis in a Patient with Hemophagocytic Lymphohistiocytosis
Annals of Dermatology
;
: 90-93, 2016.
Article
in English
| WPRIM
| ID: wpr-223546
ABSTRACT
Graft-versus-host disease (GVHD) is a common complication of bone marrow transplantation (BMT) that can be classified as acute or chronic. Chronic GVHD, which usually occurs more than 3 months after BMT, includes typical lichenoid or sclerodermatous lesions. Psoriasiform eruption is a rare clinical manifestation of chronic GVHD, and there have been no reports of psoriasiform chronic GVHD associated with hemophagocytic lymphohistiocytosis. A 33-year-old woman who was diagnosed with hemophagocytic lymphohistiocytosis 10 years ago visited our outpatient clinic with psoriasiform eruption over her entire body. She underwent allogeneic BMT 7 months previously from her sibling. Skin biopsy was performed on the lesion, and the histological features suggested GVHD. The psoriasiform lesions improved with narrow-band ultraviolet B phototherapy, with secondary vitiligo remaining on the corresponding locations.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phototherapy
/
Psoriasis
/
Skin
/
Vitiligo
/
Biopsy
/
Bone Marrow Transplantation
/
Siblings
/
Lymphohistiocytosis, Hemophagocytic
/
Ambulatory Care Facilities
/
Graft vs Host Disease
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Annals of Dermatology
Year:
2016
Type:
Article
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