The Effect of Topical Mitomycin C after Excisional Biopsy in Conjunctival-corneal Intraepithelial Neoplasia: Two cases
Journal of the Korean Ophthalmological Society
;
: 1102-1110, 2001.
Article
in Korean
| WPRIM
| ID: wpr-224147
ABSTRACT
PURPOSE:
To investigate the effect of topical Mitomycin C(MMC) as a medical adjunct to incompletely excised conjunctival-corneal intraepithelial neoplasia(CCIN) for removal of remaining neoplastic cells and prevention of recurrence.METHODS:
The authors applied postoperative topical 0.02% MMC adjunctively on 2 eyes of 2 patients with incompletely excised and histopathologically confirmed conjunctival-corneal intraepithelial neoplasia(CCIN) for 2weeks and if the lesion is not regressed, topical MMC treatment with the same regimen was added.RESULTS:
Remaining lesions were completely regressed and no recurrence has been found with follow up to 25 months and 26 months in each case.CONCLUSIONS:
Topical MMC chemotherapy would be an effective treatment modality on incompletely excised conjunctival-corneal intraepithelial neoplasia(CCIN) for removal of remaining neoplatic cells and prevention of recurrence.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Biopsy
/
Follow-Up Studies
/
Mitomycin
/
Drug Therapy
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2001
Type:
Article
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