Clinical value of serum vascular endothelial growth factor (VEGF) in ovarian diseases / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
;
: 135-141, 2007.
Article
in Korean
| WPRIM
| ID: wpr-224168
ABSTRACT
OBJECTIVE:
The aim of this study was to evaluate the concentration of serum VEGF and its relationship with the clinical parameters and the tumor markers in ovarian diseases.METHODS:
We measured the serum VEGF concentrations by ELISA in 76 patients with benign ovarian disease, as well as 9 normal volunteers, 4 patients with ovarian borderline malignancy and 53 patients with ovarian cancer.RESULTS:
There is a significant statistical difference between the serum VEGF levels in patients with benign ovarian disease (157.7+/-197.8 pg/ml) and ovarian cancer (344.7+/-372.2 pg/ml) (p<0.005).CONCLUSION:
Serum VEGF may help in the differential diagnosis between benign and malignant ovarian disease. We suggest that serum VEGF may be useful as a diagnostic tool in ovarian disease.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovarian Diseases
/
Ovarian Neoplasms
/
Enzyme-Linked Immunosorbent Assay
/
Biomarkers, Tumor
/
Vascular Endothelial Growth Factor A
/
Diagnosis, Differential
/
Healthy Volunteers
Type of study:
Diagnostic study
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
2007
Type:
Article
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