Clinical Features of Hepatitis A in Korean Adults / 대한내과학회지
Korean Journal of Medicine
;
: 685-690, 1999.
Article
in Korean
| WPRIM
| ID: wpr-224312
ABSTRACT
OBJECTIVE:
This study was aimed to characterize the clinical features and course of acute hepatitis A in Korean adults.METHODS:
One-hundred and thirteen cases of acute hepatitis A, diagnosed between Jan. 1995 to July 1998 at 6 medical centers in Korea, were reviewed retrospectively. The clinical course of 94 cases with follow-up duration longer than 3 months were analyzed.RESULTS:
The median age was 26 (16-65) years and 97.3% of the patients were under 40 years. The presumed sources of infection were identifed in 62 cases (54.9%). Among those, the leading source was ingestion of raw food. All patients showed normalization of bilirubin level within 8 weeks. The ALT levels normalized within 8 weeks in all patients except three patients (3.2%). Three patients with prolonged elevation of ALT showed second rise of ALT, suggesting a possibility of relapsing hepatitis. Prolonged fever (>38 degree C) more than 10 days was observed in 3 patients (3.2%). One case showed prolonged elevation of alkaline phosphatase (> x3 upper normal limit). No case of fulminant hepatic failure or death was observed.CONCLUSION:
The majority of cases with acute hepatitis A in Korean adults showed self-limited course with full recovery.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Bilirubin
/
Retrospective Studies
/
Follow-Up Studies
/
Liver Failure, Acute
/
Eating
/
Alkaline Phosphatase
/
Fever
/
Hepatitis
/
Hepatitis A
/
Korea
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
1999
Type:
Article
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