Accuracy of F-18 FDG PET/CT in Preoperative Assessment of Cervical Lymph Nodes in Head and Neck Squamous Cell Cancer: Comparison with CT/MRI / 핵의학분자영상
Nuclear Medicine and Molecular Imaging
;
: 309-315, 2006.
Article
in Korean
| WPRIM
| ID: wpr-224480
ABSTRACT
PURPOSE:
Accurate evaluation of cervical lymph node (LN) metastasis of head and neck squamous cell cancer (SCC) is important to treatment planning. We evaluated the diagnostic accuracy of F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) for the detection of cervical LN metastasis of head and neck SCC and performed a retrospective comparison with CT/MRI findings. MATERIALS ANDMETHODS:
Seventeen patients with pathologically proven head and neck SCC underwent F-18 FDG PET/CT and CT/MRI within 4 week before surgery. We recorded lymph node metastases according to the neck level system of imaging-based nodal classification. F-18 FDG PET/CT images were analyzed visually for assessment of regional tracer uptake in LN. We analyzed the differences in sensitivity and specificity between F-18 FDG PET/CT and CT/MRI using the Chi-square test.RESULTS:
Among the 17 patients, a total of 123 LN levels were dissected, 29 of which showed metastatic involvement. The sensitivity and specificity of F-18 FDG PET/CT for detecting cervical LN metastasis on a level-by-level basis were 69% (20/29) and 99% (93/94). The sensitivity and specificity of CT/MRI were 62% (18/29) and 96% (90/94). There was no significant difference in diagnostic accuracy between F-18 FDG PET/CT and CT/MRI. Interestingly, F-18 FDG PET/CT detected double primary tumor (hepatocellular carcinoma) and rib metastasis, respectively.CONCLUSION:
There was not statistically significant difference of diagnostic accuracy between F-18 FDG PET/CT and CT/MRI for the detection of cervical LN metastasis of head and neck SCC. The low sensitivity of F-18 FDG PET/CT was due to limited resolution for small metastatic deposits.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ribs
/
Retrospective Studies
/
Sensitivity and Specificity
/
Classification
/
Neoplasms, Squamous Cell
/
Positron-Emission Tomography
/
Electrons
/
Positron Emission Tomography Computed Tomography
/
Head
/
Head and Neck Neoplasms
Type of study:
Diagnostic study
/
Observational study
Limits:
Humans
Language:
Korean
Journal:
Nuclear Medicine and Molecular Imaging
Year:
2006
Type:
Article
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