Clinicopathological Characteristics of Ovarian Metastasis from Colorectal Cancer
Journal of the Korean Surgical Society
;
: 287-293, 2010.
Article
in Korean
| WPRIM
| ID: wpr-224919
ABSTRACT
PURPOSE:
Treatment of ovarian metastasis from colorectal cancer has been controversial. We investigated the clinicopathologic features and treatment outcomes of patients with ovarian metastasis from colorectal carcinoma.METHODS:
From January 1996 to May 2009, 567 women were treated for colorectal cancer. Of those, 23 patients were diagnosed as having ovarian metastasis. We reviewed 19 pathologically proven cases, retrospectively.RESULTS:
The incidence of ovarian metastasis was 4.0%. The number of cases involving synchronous ovarian metastases was 9 (47.4%), and 10 cases (52.6%) involved metachronous ovarian metastases. Thirteen patients had metastases located in the pelvis and 6 also had peritoneal dissemination in addition to the ovarian metastasis. Twenty (63.1%) were treated with grossly complete resection. After a median follow-up duration of 45 months (range of 6~96 months), the median survival after the diagnosis of ovarian metastasis was 40 months. The median overall survival was significantly longer in the grossly complete resection group (48.5 vs. 16 months; P=0.001). For median survival after the diagnosis of ovarian-metastasis, patients with grossly complete resection showed a significantly more favorable survival rate than the group with remnant tumors (46.5 vs 9 months; P=0.009). The survival of patients with metastases located in the pelvis was better than the group with peritoneal dissemination.CONCLUSION:
Grossly complete resection would be of help to improve the prognosis in selective patients with metastasis from colorectal cancer, especially when metastasis is located in the pelvis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pelvis
/
Prognosis
/
Colorectal Neoplasms
/
Incidence
/
Survival Rate
/
Retrospective Studies
/
Follow-Up Studies
/
Neoplasm Metastasis
Type of study:
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
Language:
Korean
Journal:
Journal of the Korean Surgical Society
Year:
2010
Type:
Article
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