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Epidemiology and Etiology of Obstructive Sleep Apnea / 대한내과학회지
Korean Journal of Medicine ; : 6-12, 2015.
Article in Korean | WPRIM | ID: wpr-225517
ABSTRACT
Obstructive sleep apnea (OSA) is one of common sleep disorders in western countries, affecting 4% of males and 2% of females. It is characterized by repeated obstruction of the upper airway during sleep, leading to intermittent hypoxemia, sympathetic activation, and sleep fragmentation. OSA is an independent risk factor for a range of medical problems, including cardiovascular disease, diabetes, depression, and cognitive dysfunctions. The etiology of OSA is complex and incompletely understood, but recent studies have shown that the development of OSA depends on the structure of the airway anatomy, the responsiveness of the upper airway dilator muscle to stimulation, and the stability of the respiratory control system. This review details the epidemiological and experimental evidence surrounding the associations between OSA and chronic diseases. Recent findings on the etiology of OSA will also be discussed.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Sleep Deprivation / Sleep Wake Disorders / Cardiovascular Diseases / Chronic Disease / Epidemiology / Risk Factors / Sleep Apnea, Obstructive / Depression / Hypoxia Type of study: Etiology study / Risk factors / Screening study Limits: Female / Humans / Male Language: Korean Journal: Korean Journal of Medicine Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Sleep Deprivation / Sleep Wake Disorders / Cardiovascular Diseases / Chronic Disease / Epidemiology / Risk Factors / Sleep Apnea, Obstructive / Depression / Hypoxia Type of study: Etiology study / Risk factors / Screening study Limits: Female / Humans / Male Language: Korean Journal: Korean Journal of Medicine Year: 2015 Type: Article