Marginal Recurrence after Radiofrequency Ablation of Hepatocellular Carcinoma: Relationship between Distance from Hepatic Capsule to Tumor and Recurrence Period
Journal of the Korean Radiological Society
;
: 171-176, 2003.
Article
in Korean
| WPRIM
| ID: wpr-225609
ABSTRACT
PURPOSE:
To examine the relationship between distance from hepatic capsule to tumor and recurrence among hepatocellular carcinoma patients in whom marginal recurrence was noted after radiofrequency ablation therapy. MATERIALS ANDMETHODS:
Between January 2000 and December 2001, hepatocellular carcinoma patients with a tumor 5 cm or less in size and located 2 cm or less from the hepatic capsule underwent radiofrequency ablation therapy. We subsequently selected 37 patients (41 tumors) in whom immediate CT demonstrated complete tumor ablation and follow-up CT showed marginal recurrence. Tumors were grouped according to their distance from the hepatic capsule Group I, adhered to the capsule; Group II, less than 1 cm from it; Group III, 1-2 cm distant. Of the 41 tumors, 22 were assigned to Group I, six to Group II, and 13 to Group III. Mean tumor size was 3.2 cm, and inter-group variation was small (Group I, 3.3 cm; Group II, 2.9 cm; Group III, 3.1 cm). Follow-up CT was used to determine marginal recurrence, and for inter-group comparison and the assessment of statistical significance, the t test was employed.RESULTS:
Marginal recurrence was noted at mean 5.5 months (2.7 months in Group I, 3.0 months in Group II, and 10.5 months in Group III). The t test revealed significant difference between Group I and III (p<0.0001) but not between Groups I and II, or II and III. If '1 cm from hepatic capsule' was the criterion for classification, and Group I and II were combined and compared with Group III, there was significant difference between the two groups (<0.0001).CONCLUSION:
Tumors which adhered to the hepatic capsule or were less than 1 cm from it recurred sooner than those situated 1-2 cm away.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Follow-Up Studies
/
Classification
/
Catheter Ablation
/
Carcinoma, Hepatocellular
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Radiological Society
Year:
2003
Type:
Article
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