Effect of Panax Ginseng Water Extract for Treatment of Male Infertility / 대한남성과학회지
Korean Journal of Andrology
;
: 94-99, 2002.
Article
in Korean
| WPRIM
| ID: wpr-226045
ABSTRACT
PURPOSE:
We previously reported that Panax ginseng water extract (PG-WE) played both preventive and therapeutic roles on testicular toxicity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in animal study, one of the most potent environmental pollutants. Thus we investigated whether PG-WE might be useful in the treatment of male infertility, because men in modern society are exposed by numerous environmental hormones. MATERIALS ANDMETHODS:
Eighteen patients with abnormal semen analysis and 8 volunteers whose semen analysis were normal as control group were enrolled in this study. Before PG-WE administration, semen analysis, hormonal study, liver and renal function test, CBC, and urinalysis were checked in all subjects. PG-WE (2.4 gm) was administered everyday for 8 weeks in both groups. Follow-up semen analysis and laboratory studies were checked at 13th week.RESULTS:
In patient group semen volume was increased (2.4 1.3 ml vs 2.6 1.6 ml, p=0.051). Semen volume as well as sperm concentration in oligospermia patient were increased but not significantly. Serum estradiol level decreased by PG-WE treatment in patient group (p=0.005). All subjects showed no toxic effect.CONCLUSIONS:
Our data suggest that Panax ginseng is a potential agent that can improve abnormal sperm parameters in infertile male patients and also improve the sperm quality in healthy men.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oligospermia
/
Semen
/
Spermatozoa
/
Volunteers
/
Water
/
Follow-Up Studies
/
Urinalysis
/
Environmental Pollutants
/
Estradiol
/
Semen Analysis
Type of study:
Observational study
/
Prognostic study
Limits:
Animals
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Andrology
Year:
2002
Type:
Article
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