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Cutaneous Extramedullary Hematopoiesis in Idiopathic Myelofibrosis / 대한피부과학회지
Korean Journal of Dermatology ; : 1060-1063, 2012.
Article in Korean | WPRIM | ID: wpr-22675
ABSTRACT
Extramedullary hematopoiesis is commonly seen in the liver, spleen and lymph nodes, but cutaneous extramedullary hematopoiesis (CEH) is very rare. CEH affects mainly children with intrauterine viral or hematologic disorders and rare manifestation of chronic myeloproliferative processes in adults. Idiopathic myelofibrosis (IM) is a chronic myeloproliferative disorder and some cases of IM have extramedullary hematopoiesis. IM is characterized by the proliferation of the endothelial cells and fibroblasts in the bone marrow, resulting in disruption of bone marrow, with subsequent migration and proliferation of the hematopoietic stem cells in other organs. We report a very rare case of cutaneous extramedullary hematopoiesis in a 74-year-old male with IM.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Spleen / Bone Marrow / Hematopoiesis, Extramedullary / Hematopoietic Stem Cells / Endothelial Cells / Primary Myelofibrosis / Fibroblasts / Liver / Lymph Nodes / Myeloproliferative Disorders Limits: Adult / Child / Humans / Male Language: Korean Journal: Korean Journal of Dermatology Year: 2012 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Spleen / Bone Marrow / Hematopoiesis, Extramedullary / Hematopoietic Stem Cells / Endothelial Cells / Primary Myelofibrosis / Fibroblasts / Liver / Lymph Nodes / Myeloproliferative Disorders Limits: Adult / Child / Humans / Male Language: Korean Journal: Korean Journal of Dermatology Year: 2012 Type: Article