Effects of Korean Red Ginseng on Cardiovascular Risks in Subjects with Metabolic Syndrome: a Double-blind Randomized Controlled Study / 가정의학회지
Korean Journal of Family Medicine
;
: 190-196, 2012.
Article
in English
| WPRIM
| ID: wpr-227509
ABSTRACT
BACKGROUND:
This study investigated the effects of Korean red ginseng (KRG) supplementation on metabolic parameters, inflammatory markers, and arterial stiffness in subjects with metabolic syndrome.METHODS:
We performed a randomized, double-blind, placebo-controlled, single-center study in 60 subjects who were not taking drugs that could affect metabolic and vascular functions. Subjects were randomized into either a KRG (4.5 g/d) group or a placebo group for a 12-week study. We collected anthropometric measurements, blood for laboratory testing, and brachial-ankle pulse wave velocity (baPWV) at the initial (week 0) and final (week 12) visits.RESULTS:
A total of 48 subjects successfully completed the study protocol. Oral administration of KRG did not significantly affect blood pressure, oxidative or inflammatory markers, or baPWV.CONCLUSION:
We found no evidence that KRG had an effect on blood pressure, lipid profile, oxidized low density lipoprotein, fasting blood glucose, or arterial stiffness in subjects with metabolic syndrome. These findings warrant subsequent longer-term prospective clinical investigations with a larger population. TRIAL REGISTRATION ClinicalTrials.gov Identifier NCT00976274
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood Glucose
/
Blood Pressure
/
Administration, Oral
/
Fasting
/
Vascular Stiffness
/
Pulse Wave Analysis
/
Panax
/
Lipoproteins
/
Lipoproteins, LDL
Type of study:
Controlled clinical trial
/
Etiology study
/
Practice guideline
/
Prognostic study
Language:
English
Journal:
Korean Journal of Family Medicine
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS