Intrauterine therapy for macrocystic congenital cystic adenomatoid malformation of the lung
Obstetrics & Gynecology Science
;
: 102-108, 2014.
Article
in English
| WPRIM
| ID: wpr-228434
ABSTRACT
OBJECTIVE:
To report on our experiences with thoracoamniotic shunting and/or the injection of a sclerosing agent (OK-432) to treat fetuses diagnosed with macrocystic congenital cystic adenomatoid malformation (CCAM) of the lung.METHODS:
A retrospective study was undertaken in six fetuses with macrocystic CCAM at our institute that had been confirmed by postnatal surgery between August 1999 and January 2012.RESULTS:
Six fetuses that had been diagnosed with macrocystic CCAM were analyzed. The median gestational age at diagnosis was 23.5 weeks (range, 19.5-31.0 weeks), and at the time of primary treatment was 24.0 weeks (range, 20.5-31.0 weeks). The mean size of the largest cyst at the initial assessment was 42.5+/-15 mm. Four fetuses were associated with mediastinal shifting, and one also showed fetal hydrops. All fetuses underwent a shunting procedure within the cysts, one case among them was also treated with OK-432. After the completion of all procedures, the mean size of the largest cyst was all decreased (14.2+/-12 mm). The median gestational age at delivery was 38.0 weeks (range, 32.4-40.3 weeks). All of the newborns underwent the surgical resection at a median age of 6 days (range, 1-136 days) and are currently doing well without any complications.CONCLUSION:
We suggest that intrauterine decompression therapy to manage fetal macrocystic CCAM is recommendable treatment for good perinatal outcome.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Picibanil
/
Prenatal Diagnosis
/
Sclerosing Solutions
/
Hydrops Fetalis
/
Cystic Adenomatoid Malformation of Lung, Congenital
/
Retrospective Studies
/
Gestational Age
/
Decompression
/
Fetal Therapies
/
Diagnosis
Type of study:
Diagnostic study
/
Observational study
Limits:
Humans
/
Infant, Newborn
Language:
English
Journal:
Obstetrics & Gynecology Science
Year:
2014
Type:
Article
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