A case of oxaliplatin-induced immune-mediated thrombocytopenia
Blood Research
;
: 61-64, 2014.
Article
in English
| WPRIM
| ID: wpr-228926
ABSTRACT
Oxaliplatin is a platinum compound used in patients with gastrointestinal malignancies. It is known to evoke a drug-induced immune-mediated thrombocytopenia, which has not been reported in Korea. We describe a 53-year-old man who developed oxaliplatin-induced immune-mediated thrombocytopenia during chemotherapy for colon cancer. Oxaliplatin-dependent IgG platelet antibodies were detected in his serum on flow cytometry. He was treated with immunoglobulin and corticosteroids without any complications. Physicians should consider oxaliplatin-induced immune-mediated thrombocytopenia, when a sudden, isolated thrombocytopenia develops during chemotherapy with oxaliplatin.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Platinum
/
Thrombocytopenia
/
Blood Platelets
/
Immunoglobulin G
/
Immunoglobulins
/
Adrenal Cortex Hormones
/
Colonic Neoplasms
/
Drug Therapy
/
Flow Cytometry
/
Korea
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Blood Research
Year:
2014
Type:
Article
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