A Case of Radiation-Induced Pemphigus
Annals of Dermatology
;
: 212-215, 1998.
Article
in English
| WPRIM
| ID: wpr-229305
ABSTRACT
Radiation induced pemphigus, as an example of induced pemphigus, is a rare disease which occurs in patients receiving radiotherapy. A 56-year-old male patient with nasopharyngeal cancer received 3 cycles of chemotherapy and radiotherapy on the neck and anterior chest areas. One month after completion of radio-therapy, eroded and crusted areas developed within the irradiation site. In spite of systemic antibiotic treatment, the skin lesions persisted and spread further to the trunk and upper extremities with new crops of bullae. He was treated with a high dose of prednisolone and the skin lesions cleared. We discuss the suggestive pathogenesis of radiation-induced pemphigus with the comparative results of immunoblotting in various variants of pemphigus.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Radiotherapy
/
Skin
/
Thorax
/
Prednisolone
/
Immunoblotting
/
Nasopharyngeal Neoplasms
/
Pemphigus
/
Cytochrome P-450 CYP1A1
/
Upper Extremity
/
Rare Diseases
Limits:
Humans
/
Male
Language:
English
Journal:
Annals of Dermatology
Year:
1998
Type:
Article
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