Atropine and Scopolamine on the Bradycardia Induced Atropine and Scopolamine / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 325-329, 1979.
Article
in Korean
| WPRIM
| ID: wpr-22947
ABSTRACT
1) Atropine and scopolamine in doses of 0. 05, 0. 1, 0, 15, 0. 2 and 0. 25 mg produced bradycardia in humans. 2) The bradycardia induced by 0. 05 and 0, 1 mg of atropine was restored to normal rhythm by 0. 2 and 0. 15 mg of atropine, respectively. 3) The bradycardia induced by 0. 05 and 0. 1 mg of scopolamine was reversed to tachycardia by 0. 2 and 0. 15 mg of scopolamine, respectively. 4) The scopolamine(0.05mg) induced bradycardia was restored to normal rhythm by atropine 0.15 mg and reversed to tachycardia by atropine 0.2mg 5) The atropine(0.1 mg) induced bradycardia was partially restored by scopolamine 0.15 and 0. 2 mg. 6) It was argued that these results were not explainable by a central vagal effect of a direct effect of atropine and scopolamine on the heart but explainable by the blocking effect of these drugs to the sympathetic ganglia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Atropine
/
Scopolamine
/
Tachycardia
/
Bradycardia
/
Ganglia, Sympathetic
/
Heart
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
1979
Type:
Article
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