When less is more: can we abandon prophylactic platelet transfusion in Dengue fever?
Annals of the Academy of Medicine, Singapore
;
: 539-545, 2011.
Article
in English
| WPRIM
| ID: wpr-229607
ABSTRACT
Dengue fever (DF) has several hematological manifestations including thrombocytopenia and increased bleeding risk. Prophylactic platelet transfusion-in the absence of major bleeding-is utilized in DF with thrombocytopenia with the intention of preventing hemorrhagic complications. However, prophylactic platelet transfusion in DF is neither standardized nor supported by clinical evidence. We conclude that risks, costs and poor resource utilization associated with prophylactic platelet transfusion in DF far outweigh any potential hematological benefit, and as such, should not constitute routine clinical practice.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Therapeutics
/
Thrombocytopenia
/
Platelet Transfusion
/
Dengue
/
Economics
/
Hemorrhage
Type of study:
Health economic evaluation
Limits:
Humans
Language:
English
Journal:
Annals of the Academy of Medicine, Singapore
Year:
2011
Type:
Article
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