Analysis of the function of vascular endothelial cells in coronary heart disease patients of blood-stasis syndrome / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 407-410, 2006.
Article
in Zh
| WPRIM
| ID: wpr-230194
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the function of vascular endothelial cell (VEC) in patients with coronary heart disease (CHD) of Xin-blood-stasis syndrome.</p><p><b>METHODS</b>Some vasoactive substances produced by VEC were detected and analyzed in patients with CHD of or without Xin blood stasis syndrome in group A (n=112) and group B (n=108) respectively, also in patients with non-CHD but of Xin-blood-stasis syndrome in group C (n=110), and healthy persons in group D (n=100), including nitric oxide (NO), endothelin (ET), angiotensin H (Ag II), soluble intercellular adhesion molecule-1 (sICAM-1) and soluble vascular cell adhesion molecule -1 (sVCAM-1).</p><p><b>RESULTS</b>The abnormality degree of ET, Ag II , sICAM-1 and sVCAM-1 in various groups showed such a tendency as group A> group B> group D (P < 0.01 or P < 0.05), while no significant difference in these criteria between group A and group C was shown (P > 0.05).</p><p><b>CONCLUSION</b>The vasoactive substances secreted by VEC are closely related to the formation and progression of CHD, and are likely to be important pathological markers of blood-stasis syndrome in CHD.</p>
Full text:
1
Index:
WPRIM
Main subject:
Physiology
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Coronary Artery Disease
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Endothelins
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Intercellular Adhesion Molecule-1
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Endothelial Cells
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Diagnosis, Differential
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Medicine, Chinese Traditional
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Metabolism
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Nitric Oxide
Type of study:
Diagnostic_studies
Limits:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
Language:
Zh
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2006
Type:
Article