Genetic status of a AB chimeric blood group family / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 417-420, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-230255
ABSTRACT
In order to study the genetic status of a rare chimeric family, some samples of A(3)B(3) family were identified by sequencing of ABO gene; flow-rSSO and PCR-SSP were used to detect loci of HLA-A, B, DRB1 genes, and multiplex amplifying with fluorescence-dye were performed for 16 short tandem repeat (STR) loci. The results indicated that two individuals from A(3)B(3) family contained more than two alleles at ABO gene, HLA-B, DRB1 and some STR loci. In conclusion, analysis of chimeric blood group by using genotyping techniques clearly demonstrating genetic status of this rare chimeric blood group promotes further elucidation of the existing state of specific genetic status.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pedigree
/
Polymorphism, Genetic
/
ABO Blood-Group System
/
HLA-A Antigens
/
HLA-B Antigens
/
HLA-DR Antigens
/
Tandem Repeat Sequences
/
Chimerism
/
Allergy and Immunology
/
HLA-DRB1 Chains
Type of study:
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2007
Type:
Article
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