Liver pathology in idiopathic portal hypertension / 中华肝脏病杂志
Chinese Journal of Hepatology
;
(12): 374-377, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-230593
ABSTRACT
<p><b>OBJECTIVE</b>To study the histopathological changes of livers in idiopathic portal hypertension (IPH).</p><p><b>METHODS</b>Liver specimens from 29 cases with idiopathic portal hypertension were studied. Histological preparations of the livers were stained with haematoxylin eosin and Masson's trichrome; reticular fibers in the liver tissues were demonstrated. The slides were also stained using some immunohistochemistry methods, and the pathological changes of the livers were analyzed.</p><p><b>RESULTS</b>The characteristic changes found in these IPH livers were dense portal fibrosis; obliteration, with or without phlebitis, of the branches of the portal vein; dilatation of the sinusoids; atrophy and nodular hyperplasia of liver cells.</p><p><b>CONCLUSIONS</b>Histopathological changes of the livers in IPH are dense portal fibrosis, portal vein branch obliteration and nodular hyperplasia of liver cells. These are the main features for a histopathological diagnosis of IPH.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Fibrosis
/
Hypertension, Portal
/
Liver
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Hepatology
Year:
2007
Type:
Article
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