A study on the targeting collect character of ferromagnetic drug carrier particles in microvasculature / 生物医学工程学杂志

ABSTRACT

The transport and capture of therapeutic magnetic particles in the human microvasculature is studied numerically. Taking into account the dominant magnetic and fluidic forces on the particles, we have shown in our study that the particles can be directed to and concentrated at the desired zone which is within a few centimeters from the surface of the body. In addition, we have analyzed the influences of the malignant tissue depth, of the nanometers-iron nuclide content in a particle, and of the blood flow velocity and blood vessel diameter upon the captured efficiency.