One case of correlation between the human herpesvirus 7 DNA load and the hemo hagocytic syndrome / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 123-125, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-231174
ABSTRACT
<p><b>OBJECTIVE</b>To research the relationship between human herpesvirus 7 (HHV-7) viral Load and the etiopathogenisis of hemophagocytic syndrome, in order to provide evidence for the clinical diagnosis of hemophagocytic syndrome and anti-virus therapy.</p><p><b>METHODS</b>Peripheral blood of patient with hemophagocytic syndrome during different treatment periods, extracted DNA, Syntheticed the primers of HHV-7, gene sequence of PCR amplified fragments detected, determined HHV-7 viral Load by Real-time fluorescent quantitative PCR and the ferritin concentration in peripheral blood detected by chemiluminescence.</p><p><b>RESULT</b>The sequence result indicated that PCR amplified fragment was a part of HHV-7 gene, the ferritin concentration viried with the load of HHV-7.</p><p><b>CONCLUSION</b>The occurrence of hemophagocytic syndrome is connetted with the load of HHV-7.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Virology
/
Herpesvirus 7, Human
/
Viral Load
/
Lymphohistiocytosis, Hemophagocytic
/
Ferritins
/
Genetics
/
Metabolism
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2011
Type:
Article
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