Research on the relationship between combined detection of RF and CCP and Chinese medical syndrome patterns of RA / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 1608-1610, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-231636
ABSTRACT
<p><b>OBJECTIVE</b>To study the objective diagnostic mechanisms on Chinese medical (CM) syndrome patterns of rheumatoid arthritis (RA), and to research different titers of rheumatoid factor (RF)/citrullinated protein antibody (CCP) in CM syndrome patterns of RA.</p><p><b>METHODS</b>Totally 230 early RA patients were assigned to five CM syndrome pattern groups, i.e., the dampness-heat blockage group (50 cases), the cold-dampness blockage group (50 cases), the Shen-qi deficiency-cold group (50 cases), the Gan-Shen yin deficiency group (40 cases), and the blood stasis blockage group (40 cases). Another 100 healthy subjects were recruited as the healthy control group. RF-IGM, RF-IGA, RF-IGG, and anti-CCP antibody were detected and compared.</p><p><b>RESULTS</b>The titers of RF-IGM, RF-IGA, RF-IGG, and anti-CCP antibody were higher in all groups than in the healthy control groups (P < 0.01). As for the 5 groups, RF-IGM, RF-IGA,RF-IGG, and anti-CCP antibody were higher in the RA active stage than in the nonactive stage. They were higher in the dampness-heat blockage group in the RA active stage than in the Shen-qi deficiency-cold group, the Gan-shen yin deficiency group, and the blood stasis blockage group.</p><p><b>CONCLUSION</b>Titers of RF-IGM, RF-IGA, RF-IGG, and anti-CCP antibody could be taken as judging indicators for differentiating objective lab indices of CM syndromes and assessing the active stage of RA.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peptides, Cyclic
/
Arthritis, Rheumatoid
/
Rheumatoid Factor
/
Autoantibodies
/
Blood
/
Case-Control Studies
/
Diagnosis
/
Allergy and Immunology
/
Medicine, Chinese Traditional
Type of study:
Diagnostic study
/
Observational study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2013
Type:
Article
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