Changes of plasma adrenomedullin level during the process from chronic bronchitis to chronic cor-pulmonale / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 195-197, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-231960
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship between the plasma adrenomedullin (ADM) levels and the extent of chronic cor-pulmonale and its underlying diseases, and explore the role of ADM in these diseases.</p><p><b>METHODS</b>Totally 26 patients with chronic bronchitis, chronic bronchitis accompanied with obstructive pneumonectasia or chronic cor-pulmonale were included respectively as clinical test group T1, T2 and T3; 26 normal people and 14 patients with pneumonia were chosen as control groups (group C1 and C2). Plasma concentration of ADM in every selected individual had been measured with specific radioimmunoassay.</p><p><b>RESULTS</b>Levels of plasma ADM in T3 were significantly higher than those in T2, and T2 than T1, C1 and C2 (P < 0.05), but there were no obvious difference between T1 and C1, between T1 and C2 (P > 0.05).</p><p><b>CONCLUSIONS</b>Plasma ADM levels can reflect the severity of the above series of diseases.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peptides
/
Pulmonary Heart Disease
/
Blood
/
Severity of Illness Index
/
Bronchitis, Chronic
/
Pulmonary Disease, Chronic Obstructive
/
Adrenomedullin
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2004
Type:
Article
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