Association study between age-related macular degeneration and R1210C mutation of CFH gene in Chinese population / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 570-572, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-232254
ABSTRACT
<p><b>OBJECTIVE</b>A R1210C mutation of complement factor H (CFH) gene has been associated with age-related macular degeneration (AMD) in Caucasian population. This study was to verify above association in Han Chinese population.</p><p><b>METHODS</b>The mutation was detected by direct sequencing in 258 patients with wet AMD and 426 matched controls.</p><p><b>RESULTS</b>The R1210C mutation has not been identified in either sample.</p><p><b>CONCLUSION</b>The R1210C mutation in CFH gene is not associated with AMD in Han Chinese population.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Complement Factor H
/
Genetics
/
Macular Degeneration
/
Mutation
Type of study:
Prognostic study
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Medical Genetics
Year:
2012
Type:
Article
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