Methuosis: a novel type of cell death / 南方医科大学学报
Journal of Southern Medical University
; (12): 1844-1847, 2013.
Article
in Zh
| WPRIM
| ID: wpr-232688
Responsible library:
WPRO
ABSTRACT
Cell death is a major physiological or pathological phenomenon in life activities. The classic forms of cell death include apoptosis, necrosis, and autophagy. Recently, a novel type of cell death has been observed and termed as methuosis, in which excessive stimuli can induce cytoplasmic uptake and accumulation of small bubbles that gradually merge into giant vacuoles, eventually leading to decreased cellular metabolic activity, cell membrane rupture and cell death. In this article, we describe the nomenclature, morphological characteristics and underlying mechanisms of methuosis, compare methuosis with autophagy, oncosis and paraptosis, and review the related researches.
Full text:
1
Index:
WPRIM
Main subject:
Autophagy
/
Vacuoles
/
Cell Death
/
Apoptosis
/
Cytoplasm
/
Necrosis
Limits:
Humans
Language:
Zh
Journal:
Journal of Southern Medical University
Year:
2013
Type:
Article