Detection of plasma cofilin protein for diagnosis of lung cancer / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1551-1553, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-232753
ABSTRACT
<p><b>OBJECTIVE</b>To detect serum content of cofilin protein in patients with lung cancer and investigate its clinical value.</p><p><b>METHODS</b>The serum content of cofilin protein was detected in 30 cases of lung cancer and 30 healthy control subjects using enzyme-linked immunosorbent assay.</p><p><b>RESULTS</b>The mean serum content of cofilin protein was 0.485∓0.465 ng/ml in patients with lung cancer and 0.203∓0.102 ng/ml in the control subjects, showing a significant difference between them (P<0.05). The content of cofilin protein in patients with stage III and IV lung cancer 0.744∓0.584 ng/ml, significantly higher than that in stage II patients (0.257∓0.126 ng/ml).</p><p><b>CONCLUSION</b>Serum cofilin protein is elevated in patients with lung cancer, especially in cases in advanced stages, suggesting its relation with lung cancer staging.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Blood
/
Enzyme-Linked Immunosorbent Assay
/
Carcinoma, Squamous Cell
/
Adenocarcinoma
/
Diagnosis
/
Actin Depolymerizing Factors
/
Lung Neoplasms
/
Neoplasm Staging
Type of study:
Diagnostic study
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2013
Type:
Article
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