Diffusion tensor imaging of the white matter tracts in preoperative patients with cerebral neoplasm / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1648-1651, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-232813
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the quantitative relationship between white matter tract (WMT) variation resulting from cerebral tumors and shifting of the fractional anisotropy (FA) index in magnetic resonance (MR) diffusion tensor imaging (DTI).</p><p><b>METHODS</b>Four female and 8 male patients aged from 21 to 62 years with brain malignancies (2 malignant lymphomas, 2 low-grade astrocytomas, and 8 high-grade cerebral gliomas) underwent conventional contrast-enhanced MR and DTI examinations before operation. Routine T(2)-weighted image, fractional anisotropic (FA) map, color-coded directional map, three-dimensional white matter tractography (WMT), and the FA index of bilateral internal capsule were obtained in every patient.</p><p><b>RESULTS</b>Fiber tractography derived from DTI was consistent with known white matter fiber anatomy. The DTI patterns in WMT altered by the tumor were categorized on the basis of FA1/FA2 ratio as follows pattern 1, FA1/FA2> or =75% with normal or only slightly decreased FA; pattern 2, 50%< or =FA1/FA2<75% with WMT displacement; pattern 3, 25%< or =FA1/FA2/50% with WMT involvement; pattern 4, FA1/FA2<25% with WMT destruction.</p><p><b>CONCLUSIONS</b>DTI allows for visualization of WMT and benefits surgical planning for patients with intrinsic brain tumor. There is a positive relationship between the bilateral FA ratio (FA1/FA2) variation and WMT alterations resulting from the tumor.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Radiation Effects
/
Brain
/
Brain Neoplasms
/
Preoperative Care
/
Diagnostic Imaging
/
Radiography
/
Reproducibility of Results
/
Sensitivity and Specificity
/
Glioblastoma
/
Diffusion Magnetic Resonance Imaging
Type of study:
Diagnostic study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2006
Type:
Article
Similar
MEDLINE
...
LILACS
LIS