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Design and manufacture of microneedles array for transdermal drug delivery / 中国医疗器械杂志
Chinese Journal of Medical Instrumentation ; (6): 33-38, 2006.
Article in Chinese | WPRIM | ID: wpr-232895
ABSTRACT
It is very important to disrupt the stratum corneum structure and to create pathways allowing transport of macromolecules, as the traditional transdermal drug delivery has been severely limited by the skin barrier. With the development of the Micro Electro-Mechanical System (MEMS), it becomes possible for microneedles array to strengthen the transdermal drug delivery. In addition to the increase of the skin permeability, it can also be used to deliver drugs into skin, such as insulin and vaccine, providing a new direction for drug delivery systems. In this paper, we review the development and applications in transdermal drug delivery of microneedles' array. The commercial prospects and recommendations for the future research work are also represented.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Administration, Cutaneous / Drug Delivery Systems / Equipment Design / Micro-Electrical-Mechanical Systems / Microinjections / Needles Language: Chinese Journal: Chinese Journal of Medical Instrumentation Year: 2006 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Administration, Cutaneous / Drug Delivery Systems / Equipment Design / Micro-Electrical-Mechanical Systems / Microinjections / Needles Language: Chinese Journal: Chinese Journal of Medical Instrumentation Year: 2006 Type: Article