New flavonoids from bioactive extract of Algerian medicinal plant Launeae arborescens

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the butanol fraction of the water/acetone extract and isolate of the new flavonoids from Launeae arboescens.</p><p><b>METHODS</b>The compounds were isolated by liquid chromatographic methods and their structures were identified by using spectroscopic analysis.</p><p><b>RESULTS</b>THE ISOLATED COMPOUNDS WERE IDENTIFIED AS 7-O-[α-rhamnopyranosyl 4',5,6-Trihydroxy flavone 1,4',5'-Di-Methoxy 7-(5″-Me Hexan)1-oyl flavanone 2, 3″-isopropyl pyrano [1″7,4″6] 3',4',5',5-Tetrahydroxy flavanone 3,5,4',5'-Tri-Hydroxy 7-(3″-Me butan) -yl flavanone 4, 5,7-Dihydroxy-2',4',5' -trimethoxy-isoflavanone 5,5,6,7,4'-tetrahydroxy flavonol 6,7-O-[α-rhamnopyranosyl-(1->6)-β-glucopyranosyl]- 4',5,7-tri-hydroxy-flavanone 7,7-O-[α-rhamnopyranosyl-(1->6)-β-glucopyranosyl] 3',5-Dihydroxy 4'-Methoxy flavanone 8.</p><p><b>CONCLUSIONS</b>The presence of different types of bioactive flavonoids in Launeae arboescens extract can explain the large ethnopharmacological uses and the potential activity of this medicinal plant.</p>