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Thrombotic Thrombocytopenic Purpura Associated with Bone Marrow Necrosis Complicating Metastatic Extra-Mammary Paget's Disease
Korean Journal of Urological Oncology ; : 82-87, 2016.
Article in Korean | WPRIM | ID: wpr-23457
ABSTRACT
As extra-mammary Paget's disease is rare and usually diagnosed at early stage when it is highly curable with surgical resection, it is much rarer to see patients with recurrent metastatic disease. Thrombotic thrombocytopenic purpura in patients with metastatic solid cancer is also a rare disease and may result from bone marrow metastasis or bone marrow necrosis. For the latter, the majority of cases are not eligible for systemic chemotherapy for rapid disease progression and poor performance status. Herein, authors report a patient with thrombotic thrombocytopenic purpura associated with bone marrow necrosis complicating extra-mammary Paget's disease who was successfully treated with docetaxel and carboplatin combination chemotherapy.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Purpura, Thrombotic Thrombocytopenic / Bone Marrow / Carboplatin / Paget Disease, Extramammary / Disease Progression / Rare Diseases / Drug Therapy / Drug Therapy, Combination / Necrosis / Neoplasm Metastasis Limits: Humans Language: Korean Journal: Korean Journal of Urological Oncology Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Purpura, Thrombotic Thrombocytopenic / Bone Marrow / Carboplatin / Paget Disease, Extramammary / Disease Progression / Rare Diseases / Drug Therapy / Drug Therapy, Combination / Necrosis / Neoplasm Metastasis Limits: Humans Language: Korean Journal: Korean Journal of Urological Oncology Year: 2016 Type: Article