Observation on clinical efficacy of combined therapy of zinc supplement and jinye baidu granule in treating human cytomegalovirus infection / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 449-451, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-234851
ABSTRACT
<p><b>OBJECTIVE</b>To explore the clinical efficacy of the combined therapy of zinc supplement and Jinye Baidu granule (JBG) on human cytomegalovirus (HCMV) infection.</p><p><b>METHODS</b>One hundred and forty patients with positive HCMV-IgM were randomly divided into four groups, with 35 cases in each group, that is, the control group (only medicated with JBG), the high-, moderate- and low-dose zinc combined groups (treated with JBG combined with zinc gluconate tablet at dose of 30 mg, 20 mg, 10 mg every day respectively). The negative conversion rate of HCMV-IgM was observed.</p><p><b>RESULTS</b>Insignificant difference in the negative conversion rate was shown in comparison of the control group with the low dose group (P > 0.05), and in comparison of the high dose with the moderate dose group (P > 0.05); however, the rate was significantly lower in the control group than that in the moderate dose and high dose group (P < 0.05).</p><p><b>CONCLUSION</b>Combined therapy of zinc supplement and JBG can significantly increase the negative conversion rate of HCMV-IgM. The optimal dosage of zinc gluconate tablet was 20 mg once a day.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Antiviral Agents
/
Zinc
/
Blood
/
Immunoglobulin M
/
Drugs, Chinese Herbal
/
Cytomegalovirus Infections
/
Cytomegalovirus
/
Therapeutic Uses
/
Drug Therapy
/
Drug Therapy, Combination
Limits:
Adult
/
Female
/
Humans
Language:
Chinese
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2005
Type:
Article
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