Application of gene mutation detection in gastrointestinal stromal tumors / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 305-308, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-234914
ABSTRACT
Gastrointestinal stromal tumors(GISTs) are the most common gastrointestinal mesenchymal tumors of the gastrointestinal tract. Most of GISTs are characterized by mutation in the c-kit or PDGFR-α genes. In recent years, detection of gene mutation in GISTs has been widely used. In addition to the contribution to the diagnosis of difficult cases, such detection also has important value in predicting the efficacy of therapeutic drugs targeting, guiding clinical treatment and evaluating the prognosis of patients. In a word, gene mutation detection should be considered as the important standard for exact diagnosis and treatment of GISTs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Proto-Oncogene Proteins c-kit
/
Receptor, Platelet-Derived Growth Factor alpha
/
Gastrointestinal Stromal Tumors
/
Gastrointestinal Neoplasms
/
Mutation
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Gastrointestinal Surgery
Year:
2015
Type:
Article
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