Correlation between serum growth differentiation factor-15 and TIMI risk scores in patients with unstable angina pectoris / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1277-1278, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-235144
ABSTRACT
<p><b>OBJECTIVE</b>To explore the correlation between serum levels of growth differentiation factor-15 (GDF-15) and Thrombolysis in Myocardial Infarction (TIMI) risk scores in patients with unstable angina pectoris (UA).</p><p><b>METHODS</b>The serum levels of GDF-15 in 97 patients with UA and 30 healthy volunteers were measured using enzyme-linked immunosorbent assay (ELISA) and compared between 3 patient groups with different TIMI scores to analyze relationship between serum GDF-15 levels and TIMI risk scores.</p><p><b>RESULTS</b>The serum levels of GDF-15 in UA patients were significantly higher than those in the healthy volunteers (P<0.01). GDF-15 levels also differed significantly between patients with different TIMI scores (P<0.01), and showed a significant positive correlation to TIMI risk scores.</p><p><b>CONCLUSION</b>Serum levels of GDF-15 can be used as an index for evaluating the severity of UA.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood
/
Severity of Illness Index
/
Thrombolytic Therapy
/
Risk Assessment
/
Drug Therapy
/
Growth Differentiation Factor 15
/
Angina, Unstable
Type of study:
Etiology study
/
Risk factors
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2011
Type:
Article
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