Clinical application of T2*GRE multiple echo sequence on articular cartilage disease in the knee / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1095-1100, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-235187
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the correlation between T2* relaxation time and the pathological changes in the knee joint of patients with osteoarthritis (OA) and analyze the changes of T2* relaxation time in early cartilage injury.</p><p><b>METHODS</b>Sixty-two patients with OA in different phases underwent magnetic resonance imaging (MRI) of the knee and the articular cartilage T2* relaxation time was recorded, with 20 young healthy volunteers as the control group.</p><p><b>RESULTS</b>Patients with mild OA showed significantly different T2* relaxation time for most of the articular cartilage from that of the healthy volunteers (P<0.05), but no such difference was found between serious OA group and the healthy volunteers. The change of T2* relaxation time of the cartilage was also associated with age, weight and body height, and the potential effects of other factors could not be excluded.</p><p><b>CONCLUSION</b>The articular cartilage shows no obvious morphological changes in early OA of the knee, a stage characterized mostly by alterations of the tissue structure and compositions. Cartilage pathologies can be the most obvious on the weight-bearing surface of the medial condyle of the femur or in the patella. T2* relaxation time measurement can be helpful in the detection of early cartilage pathologies.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Patella
/
Pathology
/
Magnetic Resonance Imaging
/
Image Enhancement
/
Cartilage, Articular
/
Case-Control Studies
/
Osteoarthritis, Knee
/
Methods
Type of study:
Observational study
/
Risk factors
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2011
Type:
Article
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