Study on chemical constituents in rhigome of Ervatamia hainanensis / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the chemical constituents of the rhizome of Ervatamia hainanensis.</p><p><b>METHOD</b>The solvent extraction and silica column chromatography were used to separate the chemical constituents, and their structures were identified by physico chemical properties and spectra analysis.</p><p><b>RESULT</b>Twelve compounds were isolated and their structures were identified as voacangine (1), ibogaine (2), ibogamine (3), coronaridine (4), 19-heyneanine (5), 19-epi-heyneanine (6), 3-hydroxyl coronaridine (7), coronaridine hydroxyindolenine (8), 3-(2-oxopropyl) coronaridine (9), vobasine (10), alpha-amyrin (11), alpha-amyrin acetate (12).</p><p><b>CONCLUSION</b>Compounds 1, 2, 6, 11 and 12 were first found from this plant.</p>