Effect of Xinmaitong capsule on serum matrix metalloproteinases-9, high sensitive C-reactive protein levels in patients with acute coronary syndrome / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 850-852, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-235306
ABSTRACT
<p><b>OBJECTIVE</b>To observe the influence of Xinmaitong capsule (XMT) on serum matrix metalloproteinases-9, high sensitive C-reactive protein levels in patients with acute coronary syndrome.</p><p><b>METHOD</b>63 cases were divided by randomized, contrastive assigned to XMT group (n = 31) and control group (n = 32). The serum levels of MMP-9 and hs-CRP before and after treatment in 12 weeks were detected.</p><p><b>RESULT</b>After treatment, the serum levels of MMP-9 in control group had no changed and the levels of hs-CRP reduced. The serum levels of MMP-9 and hs-CRP in XMT group had significantly decreased. The serum levels of MMP-9 and hs-CRP had positive correlation, but had no correlation to levels of serum lipids.</p><p><b>CONCLUSION</b>XMT decreased breakdown of matrix collagen, and inflammatory reaction in the patients of ACS, which may have effect on plaque stabilization.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plants, Medicinal
/
Triglycerides
/
Blood
/
C-Reactive Protein
/
Capsules
/
Drugs, Chinese Herbal
/
Chemistry
/
Cholesterol
/
Matrix Metalloproteinase 9
/
Therapeutic Uses
Type of study:
Controlled clinical trial
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2007
Type:
Article
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