Relationship between trauma-induced coagulopathy and progressive hemorrhagic injury in patients with traumatic brain injury / 中华创伤杂志(英文版)
Chinese Journal of Traumatology
;
(6): 172-175, 2016.
Article
in English
| WPRIM
| ID: wpr-235755
ABSTRACT
Progressive hemorrhagic injury (PHI) can be divided into coagulopathy-related PHI and normal coagu- lation PHI. Coagulation disorders after traumatic brain injuries can be included in trauma-induced coagulopathy (TIC). Some studies showed that TIC is associated with PHI and increases the rates of disability and mortality. In this review, we discussed some mechanisms in TIC, which is of great importance in the development of PHI, including tissue factor (TF) hypothesis, protein C pathway and thrombocytopenia. The main mechanism in the relation of TIC to PHI is hypocoagulability. We also reviewed some coagulopathy parameters and proposed some possible risk factors, predictors and therapies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Therapeutics
/
Blood Coagulation Disorders
/
Fibrin Fibrinogen Degradation Products
/
Thromboplastin
/
Protein C
/
Cerebral Hemorrhage
/
Epidemiology
/
Incidence
/
Risk Factors
Type of study:
Etiology study
/
Incidence study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Chinese Journal of Traumatology
Year:
2016
Type:
Article
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