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Rebleeding after Initial Endoscopic Hemostasis in Peptic Ulcer Disease
Journal of Korean Medical Science ; : 1411-1415, 2014.
Article in English | WPRIM | ID: wpr-23616
ABSTRACT
Endoscopic hemostasis is the first-line treatment for upper gastrointestinal bleeding (UGIB). Although several factors are known to be risk factors for rebleeding, little is known about the use of antithrombotics. We tried to verify whether the use of antithrombotics affects rebleeding rate after a successful endoscopic hemostasis for peptic ulcer disease (PUD). UGIB patients who underwent successful endoscopic hemostasis were included. Rebleeding was diagnosed when the previously treated lesion bled again within 30 days of the initial episode. Of 522 UGIB patients with PUD, rebleeding occurred in 93 patients (17.8%). The rate of rebleeding was higher with aspirin medication (P=0.006) and after a long endoscopic hemostasis (P<0.001). Of all significant variables, procedure time longer than 13.5 min was related to the rate of rebleeding (OR, 2.899; 95% CI, 1.768-4.754; P<0.001) on the logistic regression analysis. The rate of rebleeding after endoscopic hemostasis for PUD is higher in the patients after a long endoscopic hemostasis. Endoscopic hemostasis longer than 13.5 min is related to rebleeding after a successful endoscopic hemostasis for PUD.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Peptic Ulcer / Recurrence / Antithrombins / Aspirin / Hemostasis, Endoscopic / Upper Gastrointestinal Tract / Hemorrhage / Gastrointestinal Hemorrhage Type of study: Risk factors Limits: Female / Humans / Male Language: English Journal: Journal of Korean Medical Science Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Peptic Ulcer / Recurrence / Antithrombins / Aspirin / Hemostasis, Endoscopic / Upper Gastrointestinal Tract / Hemorrhage / Gastrointestinal Hemorrhage Type of study: Risk factors Limits: Female / Humans / Male Language: English Journal: Journal of Korean Medical Science Year: 2014 Type: Article