Application of HLAMatchmaker analysis eplets mismatch of renal transplant matching / 中国应用生理学杂志
Chinese Journal of Applied Physiology
; (6): 237-241, 2014.
Article
in Zh
| WPRIM
| ID: wpr-236337
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>Eplets mismatch based on HLAMatchmaker software evaluates the clinical application of kidney transplantation.</p><p><b>METHODS</b>In 239 cases of renal transplant,merits of methods of the traditional HLA six antigen matcheing criteria, cross reaction groups standard and Eplets mismatch based on HLAMatchmaker standard were compared respectively.</p><p><b>RESULTS</b>The number of mismatchs with three methods in 239 cases, were grouped according to low-high mismatchs. The results revealed that HLAMatchmaker algorithm could significantly increase the number of low mismatchs group 54 (22.6%), compared with the HIA group 19(7.9%) and CREGs group 32 (13.4%). The comparison was discovered statistical significance among the three groups (P<0.001), so the comparison between each group was.</p><p><b>CONCLUSION</b>HLAMachmaker of donor-recipients matching, is a more efficient, time-saving and high sensitivity matching solution to allograft renal transplantation.</p>
Full text:
1
Index:
WPRIM
Main subject:
Transplantation, Homologous
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Software
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Histocompatibility Testing
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Kidney Transplantation
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Methods
Limits:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
Language:
Zh
Journal:
Chinese Journal of Applied Physiology
Year:
2014
Type:
Article