Managing a case of extensively drug-resistant (XDR) pulmonary tuberculosis in Singapore
Annals of the Academy of Medicine, Singapore
; : 132-135, 2011.
Article
in En
| WPRIM
| ID: wpr-237328
Responsible library:
WPRO
ABSTRACT
<p><b>INTRODUCTION</b>Extensively drug-resistant tuberculosis (XDR-TB) is an emerging global health risk. We present the first case report of XDR-TB in Singapore.</p><p><b>CLINICAL PICTURE</b>A 41-year-old Indonesian lady with previously treated pulmonary tuberculosis presented with chronic cough. Her sputum was strongly acid-fast bacilli positive and grew Mycobacterium tuberculosis complex resistant to first and second-line TB medications.</p><p><b>TREATMENT</b>She received 5 months of intensive multidrug treatment without sputum smear conversion. She then underwent resection of the diseased lung. The total cost incurred amounted to over S$100,000.</p><p><b>OUTCOME</b>She achieved sputum smear/culture conversion post-surgery, but will require further medical therapy for at least 18 months.</p><p><b>CONCLUSION</b>XDRTB is poorly responsive to therapy and extremely expensive to manage. Its prevention by strict compliance to therapy is paramount.</p>
Full text:
1
Index:
WPRIM
Main subject:
Singapore
/
Sputum
/
Tuberculosis, Pulmonary
/
Microbial Sensitivity Tests
/
Directly Observed Therapy
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Drug Resistance, Multiple, Bacterial
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Delirium
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Therapeutic Uses
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Drug Therapy
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Drug Therapy, Combination
Limits:
Adult
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Female
/
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
Annals of the Academy of Medicine, Singapore
Year:
2011
Type:
Article