An 11-year review of dermatomyositis in Asian patients
Annals of the Academy of Medicine, Singapore
;
: 843-847, 2010.
Article
in English
| WPRIM
| ID: wpr-237382
ABSTRACT
<p><b>INTRODUCTION</b>Dermatomyositis (DM) is a multisystem inflammatory disease with a strong association with malignancy. We aimed to describe a series of Asian patients with DM and identify any significant clinical factors associated with malignancy.</p><p><b>MATERIALS AND METHODS</b>This was a retrospective review of a multi-racial cohort of 69 Asian patients diagnosed with DM over an 11-year period from 1996 to 2006.</p><p><b>RESULTS</b>Malignancy was detected in 15 out of 68 patients (22%), the most common of which was nasopharyngeal carcinoma (7 cases). Compared to the non-malignancy group, the malignancy-associated group was older and had more male patients. There were no statistically significant clinical, serological or laboratory factors associated with a higher risk of malignancy.</p><p><b>CONCLUSION</b>This study highlights the importance of ongoing malignancy screening especially for nasopharyngeal carcinoma in Asian patients with DM.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Paraneoplastic Syndromes
/
Pathology
/
Singapore
/
Carcinoma
/
Confidence Intervals
/
Logistic Models
/
Odds Ratio
/
Nasopharyngeal Neoplasms
/
Epidemiology
/
Retrospective Studies
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Annals of the Academy of Medicine, Singapore
Year:
2010
Type:
Article
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