Development of Fuzi precision decoction pieces (PDP) (I): Specification and quality uniformity / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3488-3495, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-237685
ABSTRACT
The specification of decoction pieces and quality uniformity are the important factors to influence the efficacy of clinical medicine. Considering the deficiency of diversity, poor quality uniformity and confusion of decoction pieces specifications, we first propose a new idea of precision decoction pieces (PDP) based on clinical demands and fresh-processed technology. In order to explain the idea, a study case of aconite SUP is provided, including the optimized specification design, processing technology, extraction effects, quality uniformity, and toxic and efficacy variation and so on. The results showed that preparing 5 mm PDP by fresh-cutting is rather simple and practicable, with high efficiency and large yield; then, this technology could significantly decrease the ingredients loss and increase the efficacy components; moreover, it was helpful for achieving the quality uniformity and best extraction effects. This work revealed the quality superiority of PDP, and provided a good strategy and example for the standard of decoction pieces specification and modernization of processing technology.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Particle Size
/
Pharmacology
/
Quality Control
/
Plant Extracts
/
Chemistry
/
Chemistry, Pharmaceutical
/
Chromatography, High Pressure Liquid
/
Aconitum
/
Methods
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2015
Type:
Article
Similar
MEDLINE
...
LILACS
LIS