Allotransplantation of spermatogonial stem cells in KM mice / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the feasibility of spermatogonial stem cell allotransplantation.</p><p><b>METHODS</b>The spermatogonial stem cell allotransplantation was performed, without the use of immune inhibitor, in KM mice of similar gene types, and the spermatogenesis in recipients' testes was evaluated. The right testes were pierced for transplantation while the left ones were taken as control.</p><p><b>RESULTS</b>Allotransplant germ cells in KM mice can recover normal function of spermatogenesis in the transplanted testis without any immune suppression.</p><p><b>CONCLUSION</b>Allospermatogonial stem cells can be transplanted successfully among KM mice.</p>