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Adult-Onset Sellar and Suprasellar Atypical Teratoid Rhabdoid Tumor Treated with a Multimodal Approach: A Case Report
Article in En | WPRIM | ID: wpr-23819
Responsible library: WPRO
ABSTRACT
We report a very rare case of sellar and suprasellar atypical teratoid rhabdoid tumor (ATRT) in a 42-year-old female patient. The tumor was removed subtotally with a transsphenoidal approach. Histopathologic study showed rhabdoid cells with prominent nucleoli and abundant cytoplasm. Immunohistochemistry for INI1 was completely negative in the tumor cells, consistent with ATRT. After surgery, she received radiotherapy including spinal irradiation with proton beam therapy and subsequent chemotherapy, with no evidence of recurrence for more than 2 years. Up to date, this is the 8th case of an adult-onset ATRT in the sellar or suprasellar region. Despite its rarity, ATRTs should be considered in the differential diagnosis of an unclear malignant sellar or suprasellar lesion in adult patients and the treatment strategies for adult ATRT patients could be differentiated from those of pediatric ATRT patients.
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Full text: 1 Index: WPRIM Main subject: Radiotherapy / Recurrence / Immunohistochemistry / Rhabdoid Tumor / Cytoplasm / Diagnosis, Differential / Drug Therapy / Proton Therapy Type of study: Diagnostic_studies Limits: Adult / Female / Humans Language: En Journal: Brain Tumor Research and Treatment Year: 2014 Type: Article
Full text: 1 Index: WPRIM Main subject: Radiotherapy / Recurrence / Immunohistochemistry / Rhabdoid Tumor / Cytoplasm / Diagnosis, Differential / Drug Therapy / Proton Therapy Type of study: Diagnostic_studies Limits: Adult / Female / Humans Language: En Journal: Brain Tumor Research and Treatment Year: 2014 Type: Article